Oncotype DX test
The Oncotype DX test, which could help women diagnosed with breast cancer avoid unnecessary chemotherapy is covered on selected Irish Life Health insurance plans. The test helps Oncologists predict the benefit of chemotherapy for particular patients diagnosed with early stage breast cancer.
The Oncotype DX breast cancer assay is a 21-gene test that predicts the patient’s likely benefit from chemotherapy as well as their likelihood of breast cancer recurrence. The test provides oncologists with more detailed, patient specific information to help them decide on the best clinical care for their patient. The Oncotype DX test examines the exact nature of an early stage breast cancer tumour and the likelihood of the condition recurring within 10 years.
How is the test done?
Consultants request the test on behalf of their patients and Irish Life Health members diagnosed with a particular form1 of breast cancer will be fully covered for the test that ordinarily costs €3,180. When the test is requested by the consultant and approved by Irish Life Health, a small amount of tissue, that has already been removed during the patient’s surgery, is sent to Genomic Health’s CLIA-certified and CAP-accredited clinical reference laboratory in the USA for testing by a team of expert pathologists. A report detailing the patient’s recurrence score is prepared and returned to the ordering physician within 9-12 calendar days for discussion with the patient. The Recurrence Score is a number between 1 and 100 that indicates the patient’s risk of recurrence and likely chemotherapy benefit.
Who is suitable?
Those suitable for the Oncotype DX test include women (and men) with early stage, oestrogen receptor positive, lymph-node negative breast cancer.
How do I access the Oncotype DX TEST?
The test must be requested by the consultant oncologist treating the patient and is subject to preauthorisation by Irish Life Health. Irish Life Health members may avail of the Oncotype DX test at the eight designated Cancer Centres and associated Private Hospitals as well as Bon Secours Hospital, Cork including;
Hospitals with the Oncotype DX service:
- Mater University
- Mater Private
- St Vincent’s Public
- St Vincent’s Private
- St James
- Mid Western Regional (Limerick)
- Waterford Regional
- University College Hospital Galway
- Bon Secours Hospital, Cork
Is it effective?
The Oncotype DX breast cancer test is the only multigene expression test available that has clinical evidence validating its ability to predict the likelihood of chemotherapy benefit as well as recurrence in early-stage breast cancer. Additionally, the test report provides quantitative scores for certain individual genes.
The Oncotype DX breast cancer test has been extensively evaluated in thirteen clinical studies involving more than 4,000 breast cancer patients worldwide, including a large validation study published in The New England Journal of Medicine and a chemotherapy benefit study published in the Journal of Clinical Oncology. To date, more than 10,000 physicians in 55 countries have ordered more than 150,000 tests.
Terms & conditions apply. Please see your Table of Cover and Membership Handbook for details.
Available on selected Irish Life Health plans